Selected Publications

Meiotic DNA breaks drive multifaceted mutagenesis in the human germ line.

R Hinch, P Donnelly, AG Hinch*.

Science (2023).

Please use the link above for free access to the final published article on the Science website (no paywall). 

See the Perspective in Science by F Baudat and B de Massy. 

Characterisation of meiotic recombination intermediates through gene knockouts in founder hybrid mice.

B Davies, G Zhang, D Moralli, S Alghadban, D Biggs, C Preece, P Donnelly, AG Hinch*.

Genome Research (2023).

The configuration of RPA, RAD51 and DMC1 binding in meiosis reveals the nature of critical recombination intermediates.

AG Hinch*, P Becker, T Li, et al.  

Molecular Cell (2020).

Factors influencing meiotic recombination revealed by whole-genome sequencing of single sperm

AG Hinch, G Zhang, P Becker, et al.  

Science (2019).

Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice. 

B Davies, E Hatton, N Altemose, JG Hussin, F Pratto, G Zhang, AG Hinch, et al.

Nature (2016).

The landscape of recombination in African Americans

AG Hinch, A Tandon, N Patterson, et al.

Nature (2011).

Molecular structures and mechanisms of DNA break processing in mouse meiosis

S Yamada, AG Hinch, H Kamido, Y Zhang, W Edelmann, S Keeney.

Genes & Development (2020).

A global reference for human genetic variation 

1000 Genomes Project Consortium

Nature (2015).

*Corresponding author.

For a full listing, please see Google Scholar